Fig. 1: Foxk1 and Foxk2 promote cardiomyocyte proliferation.
From: Foxk1 and Foxk2 promote cardiomyocyte proliferation and heart regeneration
A Western blot and quantitative analysis of FOXK1 and FOXK2 expression in wild-type mouse cardiomyocytes at different ages (n = 3 per group). B, C Representative images and quantitative analysis of co-immunostaining of α-actinin (red) and pH3 (green) (B), as well as Ki67 (green) (C), indicated by yellow arrows. in primary cardiomyocytes transfected with siRNA to target Foxk1 (siFoxk1), Foxk2 (siFoxk2), or a scramble negative control (siNC) (n = 4 per group). D–I Representative images and quantitative analysis of co-immunostaining of α-actinin (red) and pH3 (green) (D, G), Ki67 (green) (E, H), and Aurora B (green) (F, I) in primary cardiomyocytes overexpressed Foxk1 or Foxk2 with adenovirus (n = 4 per group). Data are presented as mean ± SEM; p values determined by one-way ANOVA with Bonferroni multiple comparisons test (A–C and G–I). Source data are provided as a Source Data file.
