Fig. 5: RNA sequencing analysis. | Nature Communications

Fig. 5: RNA sequencing analysis.

From: Injectable bioadhesive and lubricating hydrogel with polyphenol mediated single atom nanozyme for rheumatoid arthritis therapy

Fig. 5

A The different changes of the expression of genes (Group 2 v.s. Group 1). B The different changes of the expression of genes (Group 3 v.s. Group 1) (C) Venn diagram of differentially expressed genes among the three groups. D GO enrichment of sole differentially expressed genes in Group 3. BP, biological processes. CC, cellular component. MF, molecular functions. E GSEA analysis of Foxo signaling pathway, Lysosome, osteoclast differentiation, TNF signaling pathway of DAGQD@Cu-SO3−/DA-HA hydrogel. F Heatmap analysis of differentially expressed genes involved in anti-oxidative stress, autophagy, repairment, inflammation. G Illustrating the potential mechanism by which DAGQD@Cu-SO3−/DA-HA hydrogel enhances cartilage repair and suppresses inflammation.

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