Fig. 2: PE Baseline model results, interpretation, and evaluation. | Nature Communications

Fig. 2: PE Baseline model results, interpretation, and evaluation.

From: Predicting interval from diagnosis to delivery in preeclampsia using electronic health records

Fig. 2

A The bar plots of C-indices from the original Cox-nnet models (red) and feature-reduced clinically informative model (blue), on the UM cross-validation(5 technical replications, error bars represent median ±SD) and UM hold-out test set and UF test set. B, E The survival curves and 95% CI (mean ±1.96SEM) of high-risk (top 25%), intermediate-risk (middle 50%) and low-risk groups (bottom 25%), categorized by predicted PI from the reduced baseline model in A on (B) hold-out UM test data and (E) UF test data. C, F ROC curves of prediction delivery time within 2 days, 7 days and 14 days using results from reduced baseline model on (C) UM hold-out test data and (F) UF test data. D The ln-transformed permutation importance scores of features in the feature-reduced baseline model. A positive sign indicates that a higher value in feature is associated with a shorter diagnosis-to-delivery time and a negative sign means an extension of diagnosis-to-delivery time. Color represents p-values of two-sided univariate Cox-PH test. G–L The distribution of diagnosis gestational age, sPE rate and PE in prior pregnancy rate, in associations with delivery gestational week (G–I) and time (days) to delivery (J–L), represented by different colors.

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