Fig. 2: Synthetic scope of nickel catalyzed N,N-dimethylation of bromoarenes.
From: Nickel catalyzed C-N coupling of haloarenes with B2N4 reagents
A The functional group tolerance of para-substituted haloarenes; B Variation of haloarene coupling partner; C Variation of heterohaloarene coupling partner. Reaction condition: substrates (0.2 mmol, 1.0 equiv.), Ni(acac)2 (0.02 mmol, 10 mol%), B2(NMe2)4 (0.2 mmol, 1.0 equiv.), DMF (0.5 mL), stirring at 80 °C for 24 h. Yields are reported for material obtained following purification and isolation.
