Fig. 4: Blood collection tubes impact release of immune cell RNA over time. | Nature Communications

Fig. 4: Blood collection tubes impact release of immune cell RNA over time.

From: Blood collection tube and RNA purification method recommendations for extracellular RNA transcriptome profiling

Fig. 4

Colored cells represent adjusted p-values < 0.05 from beta regression models with random effects for all cell types. Tukey's method was used for pairwise comparisons (two-sided testing) while correcting for multiple testing. P-values smaller than the minimum representable value in R (1e-16) are annotated as < 1e-16. Non-significant p-values point towards blood collection tube stability over time. T0=immediate blood processing, T04, T16, T24, T72=plasma prepared 4, 16, 24 and 72 hours after blood draw, respectively. Note that different donors were sampled and that tubes were processed at different time intervals for preservation and classic tubes.

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