Fig. 1: Under DSS induced colitis wild-type and ko mice comparison. | Nature Communications

Fig. 1: Under DSS induced colitis wild-type and ko mice comparison.

From: Balance between bile acid conjugation and hydrolysis activity can alter outcomes of gut inflammation

Fig. 1

a Experimental animal model in the Baat−/− KO mice versus wild-type mice under DSS treatment for 7 days (n = 4–5). b Weight changes during the experiment. c Daily DAI scores. d Example images of the colons from each group of mice. e The colon lengths of each animal. f Representative photomicrographs of H&E-stained (original magnification, ×100, scale bar = 100 μm). g Histology scores with representative H&E staining. Data in (b, c) expressed as the mean ± SEM; n = 4–5 animals per group; all boxplots are the interquartile range, center line is the median, with the whiskers denoting minima and maxima; statistics analyzed by one-way ANOVA with Tukey’s post hoc, and *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

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