Fig. 5: Characterizations of BSHs in IBD cohorts. | Nature Communications

Fig. 5: Characterizations of BSHs in IBD cohorts.

From: Balance between bile acid conjugation and hydrolysis activity can alter outcomes of gut inflammation

Fig. 5

a, b The alpha diversity of BSHs in IBD patients and healthy controls, which was measured using the Shannon index and Observed BSHs. c The β-diversity of BSHs was measured by principal coordinate analysis (PCoA) based on Bray-Curtis dissimilarity. d The cumulative relative abundance of BSHs in IBD patients and healthy controls. eg Taxonomic characterization of BSHs at phylum, family, and genus levels. hk Examples of significant differing BSHs in IBD compared to healthy controls. Data was analyzed by two-sided Wilcox rank-sum test followed by BH correction, and *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, sample sizes available in methods. All boxplots are the interquartile range, center line is the median, with the whiskers denoting minima and maxima.

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