Table 1 Left and right amygdala activity in response to fearful vs neutral faces predicts concurrent and future depressive symptomatology
From: Perinatal SSRI exposure impacts innate fear circuit activation and behavior in mice and humans
Predictor | Outcome | At time of MRI | 1 year post MRI | ||||
|---|---|---|---|---|---|---|---|
St. Beta | PFDR | PBONF | St. Beta | PFDR | PBONF | ||
Left Amygdala | Anxiety symptoms | 0.12 | 2.78 × 10−7 | 8.33 × 10−7 | −0.01 | 0.69 | 1 |
Depressive symptoms | 0.11 | 1.86 × 10−8 | 3.71 × 10−8 | 0.05 | 0.024 | 0.049 | |
Internalizing Symptoms | 0.06 | 3.98 × 10−4 | 1.99 × 10−3 | −0.004 | 0.79 | 1 | |
Externalizing Symptoms | 0.004 | 0.83 | 1 | −0.01 | 0.63 | 1 | |
Right Amygdala | Anxiety symptoms | 0.07 | 1.22 × 10−3 | 7.34 ×10−3 | 0.01 | 0.63 | 1 |
Depressive symptoms | 0.12 | 1.86 × 10−8 | 2.54 × 10−8 | 0.08 | 1.87 × 10−4 | 1.87 × 10−4 | |
Internalizing Symptoms | 0.08 | 7.97 × 10−7 | 3.19 × 10−6 | 0.02 | 0.63 | 1 | |
Externalizing Symptoms | −0.02 | 0.41 | 1 | ||||
