Fig. 5: Locus zoom plots for UNC13A and TNIP1 loci. | Nature Communications

Fig. 5: Locus zoom plots for UNC13A and TNIP1 loci.

From: Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing

Fig. 5

A Genetic colocalization between the UNC13A locus in FTLD (meta-analysis) and ALS signal. B Genetic colocalization between the TNIP1 locus in FTLD (meta-analysis) and ALS. C Genetic colocalization between the TNIP1 locus in FTLD (meta-analysis) and ADRD. For A, B, C, chromosome position is located on the x-axis, and −log10 transformed raw two-sided P is represented on the y-axis. Each dot represents a SNV tested in the dataset for its association with disease status. Purple diamonds are the index SNVs reported. Linkage disequilibrium with index SNV is indicated by r2.

Back to article page