Fig. 3: Substrate scope for the formal C(sp3)–O bond insertion.
From: Ligand-controlled divergent asymmetric C(sp3)−H and C(sp3)−O insertion via vinyl cations
Reaction conditions: 1 (0.15 mmol), Cu(CH3CN)4PF6 (0.015 mmol), L10 (0.018 mmol), NaBArF4 (0.018 mmol), DCE (2 mL), 0 °C, N2, 1–91 h, in Schlenk tubes; yields were those for the isolated products; ees were determined by HPLC analysis; ratios of 3/2 were measured by 1H NMR using 1,3,5-trimethoxybenzene as the internal standard. a30 °C. b15 °C. cBy using L11 as chiral ligand.
