Fig. 6: Correlation between pretreatment skin gene expression, blood cytokine levels, and disease severity after dupilumab treatment. | Nature Communications

Fig. 6: Correlation between pretreatment skin gene expression, blood cytokine levels, and disease severity after dupilumab treatment.

From: An unbiased tissue transcriptome analysis identifies potential markers for skin phenotypes and therapeutic responses in atopic dermatitis

Fig. 6

Analysis of pretreatment levels of (A) skin metagene expression, (B) marker gene expression of SKITm10, and (C) blood cytokines. The x-axis represents the averaged values of AD disease severity score (mEASI) after 5 and 6 months of dupilumab treatment, and the r and p indicate the correlation coefficient and the significance obtained through Spearman’s correlation analysis, respectively. n (samples) = 19 (lesional AD skin), 15 (non-lesional AD skin), 19 (blood). *p < 0.01, †p < 0.05. Source data are provided as a Source Data file.

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