Fig. 8: Long-term observation of skin metagenes and blood cytokines in dupilumab-treated patients. | Nature Communications

Fig. 8: Long-term observation of skin metagenes and blood cytokines in dupilumab-treated patients.

From: An unbiased tissue transcriptome analysis identifies potential markers for skin phenotypes and therapeutic responses in atopic dermatitis

Fig. 8

A Dynamics of skin metagene expression and blood cytokines in individual patients during the long-term course of dupilumab treatment. Green highlighted shadows represent the 95% CI for the mean expression in healthy individuals. B Transition in relative values compared with the baseline skin metagene expression and blood cytokines in four poorly responding patients. C Clinical images of the four poorly responding patients before and after treatment. No apparent changes in clinical phenotypes were observed during the course of treatment.

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