Fig. 6: Comparison of binding orientations of DLAM5, DLAM3, and DLAM1 within human and mouse TLR4/MD-2 complexes.
From: Structural insight into TLR4/MD-2 activation by synthetic LPS mimetics with distinct binding modes
Superimposition of a DLAM5 and DLAM3 in h- and mTLR4/MD-2 complex, b DLAM3 and DLAM1 in h- and mTLR4/MD-2 complex, c DLAM5 and DLAM1 in h- and mTLR4/MD-2 complex. In the bottom panel, only the αGlcN(1↔1)αMan backbone is shown for clarity and the lipid chains are omitted. The colors of DLAMs are consistent with Fig. 2c.
