Table 1 Clinical features of all patients

From: Long-Term Efficacy of Pembrolizumab and the Clinical Utility of ctDNA in Locally Advanced dMMR/MSI-H Solid Tumors

Clinical features

N (%)

Surgery

No

18 (51.4%)

Yes

17 (48.6%)

Primary tumor type

R-sided CRC

13 (37.1%)

L-sided CRC

6 (17.1%)

Rectal

8 (22.9%)

Brain

1 (2.9%)

Duodenal

2 (5.9%)

Endometrial

1 (2.9%)

Gastric

1 (2.9%)

Pancreas

2 (5.9%)

Ampullary

1 (2.9%)

T4

Unable to assess

5 (14.3%)

No

13 (37.1%)

Yes

17 (48.6%)

Nodal involvement

Unable to assess

10 (28.6%)

No

8 (22.9%)

Yes

17 (46.8%)

BRAF V600E status (CRC only)

Unable to assess

1 (3.7%)

Wild type

13 (48.1%)

Mutated

13 (45.7%)

Baseline ctDNA status

Negative

19 (54.3%)

Positive

16 (48.6%)

Cleared ctDNA (pre-pembrolizumab ctDNA(+); post-pembrolizumab ctDNA(-))

Unable to assess

2 (12.5%)

Yes

9 (56.3%)

No

5 (31.3%)