Fig. 3: Biochemical characterization of SARS-CoV-2 PLpro mutants.
From: Identification of naturally occurring drug-resistant mutations of SARS-CoV-2 papain-like protease

a DSF assay to characterize the thermal stability of PLpro mutants. Error bars denote mean ± SD of four biological replicates. b Enzymatic activity of PLpro mutants. The dashed line at the bottom indicates a 10-fold reduction compared to WT, The values are the mean of two biological replicates. Source data are provided as a source data file.