Fig. 4: Functional attributes of the adult Yanomami skin microbiome are distinct from western individuals.
From: Yanomami skin microbiome complexity challenges prevailing concepts of healthy skin
A Observed richness and diversity (Shannon index) of functional potential (3512 pathways assigned by MetaCyc) of the Yanomami (RAC, n = 5) and western HMP (RAC, n = 16) skin microbiome. (Wilcoxon test, two-sided, p-value: ***<0.001, **<0.01; p = 9.83E-05 and 0.00118, respectively). Boxplots: median, 1st- 3rd quartiles, whiskers min/max, outliers (1.5 × IQR). B Functional potential composition (PERMANOVA two-sided p < 0.05 of Bray-Curtis dissimilarity; pathways assigned by MetaCyc at secondary pathway classes) of Yanomami (n = 5) and western HMP (n = 16) RAC samples. C Most differential functional secondary pathway classes in RAC samples (LEfSe; Kruskal Wallis p < 0.05; pairwise Wilcoxon two-sided p < 0.05, LDA cutoff=2). D Most differential functional secondary pathway classes of active microbiota in chest (RNA) samples of Yanomami adults (n = 4) and western expeditioner (n = 3) samples (LEfSe; Kruskal Wallis p < 0.05; pairwise Wilcoxon two-sided p < 0.05, LDA cutoff=2).
