Table 2 Intraoperative variables
Levosimendan (n = 115) | Placebo (n = 113) | p Value | ||
|---|---|---|---|---|
Time of surgery, mean (SD) | 241 (109) | 233 (92) | 0.536 | |
Time of anesthesia, mean (SD) | 283 (111) | 278 (93) | 0.730 | |
Type of surgery, n (%) | General | 65 (57) | 75 (66) | 0.211 |
Urology | 49 (43) | 37 (34) | 0.162 | |
Anesthetic management, mean (SD) if used | Propofol, mg | 208 (251) | 185 (253) | 0.496 |
Fentanyl, µg | 850 (460) | 850 (450) | 0.786 | |
Phenylephrine, mg | 0.4 (0.4) | 0.3 (0.3) | 0.166 | |
Norepinephrine, mg | 1.5 (1.5) | 1.0 (0.9) | 0.007 | |
Fluids management, n (%) and mean (SD) if used | Crystalloids, mL | 3190 (1435) | 2740 (1305) | 0.317 |
Albumin, n (%) | 65 (56) | 55 (48) | 0.292 | |
Albumin, mL | 328 (377) | 291 (284) | 0.544 | |
Blood transfusion, n (%) | 25 (22) | 22 (19) | 0.795 | |
Blood transfusion, mL | 884 (430) | 697 (466) | 0.161 | |
Blood loss, mL | 1067 (950) | 899 (839) | 0.349 | |
Urinary output, mL | 500 (490) | 534 (433) | 0.631 | |
Blood pressure, mean (SD) | TWA MAP, mmHg | 77 (6) | 80 (6) | 0.001 |
TWA systole, mmHg | 122 (12) | 123 (12) | 0.806 | |
TWA diastole, mmHg | 57 (7) | 58 (6) | 0.374 | |
Hemodynamic, mean (SD) | TWA SV, mL | 78 (31) | 79 (39) | 0.315 |
TWA CI, L | 3.1 (4.9) | 3.1 (4.6) | 0.320 | |
