Fig. 2: Exploration of substrate scope 1.
From: Ligand-controlled regiodivergent and enantioselective hydrophosphorylation of styrenes by palladium
aReaction condition A: [a] 1 (0.22 mmol), 2a (0.2 mmol), (PhO)2P(O)OH (25 mol%), [Pd(allyl)Cl]2 (3 mol%) and PC10 (15 mol%) in DCM (1 ml) at 100 °C for 24 h. [b] 15 mol% TsOH·H2O was used instead of (PhO)2P(O)OH. Reaction condition B: 1 (0.22 mmol), 2a (0.2 mmol), (PhO)2P(O)OH (30 mol%), Pd(OAc)2 (6 mol%) and rac-BINAP (15 mol%) in dioxane (0.6 ml) at 80 °C for 24 h.
