Table 2 The association of baseline frailty status with risks of incident CVD

From: Frailty and depressive symptoms in relation to cardiovascular disease risk in middle-aged and older adults

 

HRS

CHARLS

SHARE

ELSA

MHAS

Pooled

 

HR (95%CI)

p

HR (95%CI)

p

HR (95%CI)

p

HR (95%CI)

p

HR (95%CI)

P

HR (95%CI)

p

Model 1

1.60 (1.49, 1.72)

<0.001

1.52 (1.37, 1.69)

<0.001

1.81 (1.70, 1.93)

<0.001

1.83 (1.65, 2.04)

<0.001

1.65 (1.48, 1.84)

<0.001

1.66 (1.60, 1.72)

<0.001

Model 2

1.64 (1.53, 1.77)

<0.001

1.54 (1.39, 1.72)

<0.001

1.78 (1.67, 1.90)

<0.001

1.82 (1.63, 2.02)

<0.001

1.64 (1.47, 1.83)

<0.001

1.67 (1.61, 1.73)

<0.001

Model 3

1.64 (1.52, 1.76)

<0.001

1.55 (1.39, 1.72)

<0.001

1.78 (1.67, 1.89)

<0.001

1.81 (1.63, 2.02)

<0.001

1.64 (1.47, 1.83)

<0.001

1.67 (1.61, 1.74)

<0.001

Model 4

1.51 (1.40, 1.63)

<0.001

1.54 (1.38, 1.71)

<0.001

1.67 (1.57, 1.78)

<0.001

1.77 (1.59, 1.98)

<0.001

1.63 (1.46, 1.82)

<0.001

1.60 (1.54, 1.66)

<0.001

  1. HRS Health and Retirement Study, CHARLS China Health and Retirement Longitudinal Study, SHARE Survey of Health, Ageing and Retirement in Europe, ELSA English Longitudinal Study of Ageing, MHAS Mexican Health and Aging Study. Model 1 adjusted for age and sex, Model 2 further adjusted education, employment, Model 3 further adjusted marital status and co-residence with children, Model 4 was fully adjusted, further controlling smoking, drinking, social activity, and physical activity. In the SHARE and Pooled cohorts, we controlled the different country.
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