Fig. 1: SCALPEL pipeline quantifies transcript isoforms at the single-cell level.
From: Quantification of transcript isoforms at the single-cell level using SCALPEL
a Schematic representation of SCALPEL function. SCALPEL decomposes conventional scRNA-seq data mapped to a gene to the different isoforms that are expressed. b SCALPEL Nextflow pipeline diagram. SCALPEL is composed of four workflows performing (1) annotation preprocessing (black line); (2) read preprocessing to discard artifacts and reads derived from pre-mRNAs (blue line); (3) quantification of isoforms in individual cells (green line); and (4) characterization of differential isoform usage (orange line).
