Fig. 4: Extended synthetic applications. | Nature Communications

Fig. 4: Extended synthetic applications.

From: LMCT-driven electron relay unlocks alcohols as tunable reductants for nickel-catalyzed cross-electrophilic couplings

Fig. 4

Unless otherwise noted, reactions were performed with aryl halide (0.2 mmol), alkyl halide (0.1 mmol), [Ce] (0.01 mmol), DPA (0.002 mmol), [Ni] (0.002 mmol), 4-Me-pyridine (0.04 mmol), Na3PO4 (0.3 mmol) and pinacol (0.5 mmol) in 0.5 mL MeCN, LEDs (λmax = 395 nm, 0.8 W/cm2) at 20 oC. Isolated yields were given, er values were determined by HPLC analysis. bMeCN/THF (4/1, 0.2 M). c2 eq. acetonephenonepinacol. dMeCN/THF (3/2, 0.1 M) was used. e8 mol% Ni(acac)2, 8 mol% chiral ligand, 6 mol% DPA.

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