Fig. 6: Evaluation of identified gene-tissue pairs. | Nature Communications

Fig. 6: Evaluation of identified gene-tissue pairs.

From: Uncovering causal gene-tissue pairs and variants through a multivariate TWAS controlling for infinitesimal effects

Fig. 6

A The colocalized proportions of causal credible sets (under two criteria) yielded by TGVIS and TGFM, respectively. B The numbers and proportions of causal cis-genes in the list of FDA-approved drug-target genes provided by Trajanoska et al., identified by TGVIS (left) and TGFM (right), respectively. C The number of significant pGenes in univariable MR analysis and the ratio of significant pGene in univariable MR analysis divided by significant eGenes/sGenes in eQTL/sQTL analysis. Source data are provided as a Source Data file. The figure was created in BioRender. Yang, Y. (2025) https://BioRender.com/ouhjfzd.

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