Fig. 2: Preparation and characterization of engineered stEiNS. | Nature Communications

Fig. 2: Preparation and characterization of engineered stEiNS.

From: Epigenetic modulation with nanosatellite triggers tumoricidal immunity for hepatocellular carcinoma treatment

Fig. 2

a schematic illustration of the preparation of dynamic-locking stEiNS. b Transmission electron microscopy imaging of stEiNS, enlarged stEiNS, and H2O2-treated stEiNS (n = 3 independent experiments). c Particle size changes of tDML, sPPN, and stEiNS determined by dynamic light scattering (DLS) with the photographs of EiNS and stEiNS (n = 3 independent experiments). d Zeta potential alterations of tDML, sPPN, and stEiNS determined with DLS (n = 3 independent experiments). e Agarose gel electrophoresis of sPPN (n = 3 independent experiments). f UV absorption spectra of TMP195, DML, and tDML, sPPN, and stEiNS. g 1H NMR changes of PPN under an in vitro simulated tumor local high concentration H2O2 environment. h In vitro drug release profiles of free TMP195, tDML, and tEiNS (n = 3 independent experiments). (i) Storage stability of stEiNS in PBS at 4 °C. Data are expressed as mean ± SD.

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