Fig. 4: Validation of CausCell’s causal structure consistency in counterfactual generation. | Nature Communications

Fig. 4: Validation of CausCell’s causal structure consistency in counterfactual generation.

From: Causal disentanglement for single-cell representations and controllable counterfactual generation

Fig. 4

a The detailed schematic framework of counterfactual generation in CausCell. b The differences between CausCell_IND and CausCell when performing the counterfactual generation. c PBAGenesScore values obtained for various intervention-associated cells generated by CausCell without incorporating a causal structure (CausCell_IND). d PBAGenesScore values produced for various intervention-associated cells generated by the CausCell version incorporating the causal structure. Source data are provided as a Source Data file. Credit: all of these concept-related icons in (a), except for cell icons, https://smart.servier.com/. The hammer icon in (b), https://www.flaticon.com/.

Back to article page