Fig. 2: Scope of the electrochemical copper-catalyzed asymmetric cyanoesterification.
From: Asymmetric cyanoesterification of vinylarenes by electrochemical copper catalysis
All yields are of isolated products. Unless otherwise noted, reaction conditions were as follows: alkene (0.15 mmol, 1.0 equiv), TMSCN (2.0 equiv), 5 (2.0 equiv), Cu(OTf)2/6 (1.0/3.0 mol %), TBAPF6 (2.0 equiv), AcOH (1.0 mmol), MeCN (3.0 mL), carbon felt as the anode, Pt as the cathode, under N2, in an undivided cell, 9.0 mA, for 4 h.
