Fig. 1: dMterf4 RNAi-mediated mitochondrial defect downregulates lysosomal LManVI mRNA level. | Nature Communications

Fig. 1: dMterf4 RNAi-mediated mitochondrial defect downregulates lysosomal LManVI mRNA level.

From: Impaired mitochondria-initiated crosstalk with lysosomes reciprocally aggravates mitochondrial defect through LManVI

Fig. 1

a RNA-seq showed that knockdown of dMterf4 significantly downregulated LManVI mRNA level (10 specific genotype fly thoraxes were mixed for RNA-seq). b RT-qPCR result showed that the mRNA level of LManVI was reduced in dMterf4 knockdown flies (n = 3 biological replicates, 10 specific genotype fly thoraxes were mixed for each replicate, data points indicate biological replicates). The error bars are mean ± SD. For the statistics, two-tailed unpaired t-test was used. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns means no significant difference. The differential gene expression analysis of dMterf4 RNAi flies was shown in the Supplementary Data 1. Source data was provided as a Source Data file.

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