Table. 1 Baseline characteristics of the SA-AKI cohort

From: Single urinary extracellular vesicle proteomics identifies complement receptor CD35 as a biomarker for sepsis-associated acute kidney injury

Baseline characteristics

Non_AKI (n = 44)

AKI (n = 70)

p-value

Age (year)

74.000

(64.000–83.000)

74.500 (60.000–80.250)

0.724

Max_Scr (mg/dl)

0.705

(0.525–0.885)

1.933

(1.530–2.589)

3.0E−15

Min_eGFR (mL/min/1.73 m2)

94.988

(82.375–115.438)

30.044 (23.053–40.684)

1.0E−15

Procalcitonin (ng/ml)

0.280

(0.101–1.540)

8.180

(1.208–30.000)

4.3E−9

HCRP (mg/L)

57.430

(20.328–91.683)

114.380 (60.850–201.825)

3.0E−4

Urine (ml/24 h)

1800.000 (1490.000–2150.000)

1080.000 (798.000–1460.000)

2.1E−7

Hemoglobin (g/L)

109.500

(98.500–119.250)

103.500 (89.000–124.000)

0.412

SOFA

10.000

(8.000–12.000)

11.000 (9.000–13.000)

0.025

Gender (%)

  

0.892

Male

29 (65.91%)

47 (67.14%)

 

Female

15 (34.09%)

23 (32.86%)

 

AKI stage (%)

  

1.0E−15

0

44 (100%)

 

1

29 (41.4%)

 

2

31 (44.3%)

 

3

10 (14.3%)

 

Hypertension (%)

  

0.86

No

24 (54.55%)

37 (52.86%)

 

Yes

20 (45.45%)

33 (47.14%)

 

Diabetes (%)

  

0.637

No

27 (61.36%)

46 (65.71%)

 

Yes

17 (38.64%)

24 (34.29%)

 

Smoking (%)

  

0.755

No

32 (72.73%)

49 (70.00%)

 

Yes

12 (27.27%)

21 (30.00%)

 

Cardiovascular diseases (%)

  

0.753

No

27 (61.36%)

45 (64.29%)

 

Yes

17 (38.64%)

25 (35.71%)

 

Mechanical. Ventilation (%)

  

0.057

No

25 (56.82%)

27 (38.57%)

 

Yes

19 (43.18%)

43 (61.43%)

 

Catecholamines (%)

  

0.021

No

22 (50.00%)

20 (28.57%)

 

Yes

22 (50.00%)

50 (71.43%)

 

Source.of.infection (%)

  

0.037

Bacteria

18 (40.91%) 

36 (51.43%)

 

Virus

1 (2.27%)

9 (12.86%)

 

Fungus

9 (20.45%)

5 (7.14%)

 

Undetected

16 (36.36%)

20 (28.57%)

 
  1. Continuous variables were analyzed using Mann–Whitney U two-sided statistics, and categorical variables were assessed with two-sided chi-square tests.
  2. AKI Acute kidney injury, eGFR estimated Glomerular filtration rate, Scr Seurm creatine, CRP Hypersensitive C-reactive protein, Max_Scr maximum serum creatinine after admission, Min_eGFR Minimum estimated glomerular filtration rate after admission.