Table. 2 Baseline characteristics of the E-AKI cohort

From: Single urinary extracellular vesicle proteomics identifies complement receptor CD35 as a biomarker for sepsis-associated acute kidney injury

Baseline characteristics

Non_AKI

(n = 46)

Subclinical AKI

(n = 26)

p-value

Age (year)

73.000 (68.000–78.500)

69.000

(59.000–77.500)

0.263

Max_Scr (mg/dl)

0.735 (0.585–0.899)

2.368

(1.559–2.866)

1.0E−15

eGFR (mL/min/1.73m2)

91.112 (78.960–100.349)

27.061

(20.308–39.360)

4.0E−15

Procalcitonin (ng/ml)

2.524 (0.570–6.275)

8.753

(0.960–16.419)

0.023

Hs-CRP (mg/L)

55.460 (25.290–103.880)

104.810

(68.525–162.612)

0.040

Urine (ml/24 h)

1580.000 (1170.000–1885.000)

1090.000 (972.500–1406.250)

0.005

Hemoglobin (g/L)

108.000 (93.500–113.500)

103.000

(82.500–111.250)

0.275

SOFA

9.000

(7.000–11.000)

9.000

(7.250–10.000)

0.63

Gender (%)

  

0.843

Male

29 (63.04%)

17 (65.38%)

 

Female

17 (36.96%)

9 (34.62%)

 

AKI stage (%)

   

0

46 (100.00%)

1.0E-15

1

11 (42.31%)

 

2

11 (42.31%)

 

3

4 (15.38%)

 

Hypertension (%)

  

0.421

No

24 (52.17%)

11 (42.31%)

 

Yes

22 (47.83%)

15 (57.69%)

 

Diabetes (%)

  

0.488

No

32 (69.57%)

16 (61.54%)

 

Yes

14 (30.43%)

10 (38.46%)

 

Smoking (%)

  

0.826

No

38 (82.61%)

22 (84.62%)

 

Yes

8 (17.39%)

4 (15.38%)

 

Cardiovascular diseases (%)

  

0.411

No

31 (67.39%)

15 (57.69%)

 

Yes

15 (32.61%)

11 (42.31%)

 

Source of infection (%)

  

0.113

Bacteria

18 (39.13%)

16 (61.54%)

 

Virus

6 (13.04%)

4 (15.38%)

 

Fungus

6 (13.04%)

0 (0.00%)

 

Undetected

16 (34.78%)

6 (23.08%)

 

Mechanical ventilation (%)

  

0.53

No

23 (50.00%)

11 (42.31%)

 

Yes

23 (50.00%)

15 (57.69%)

 

Catecholamines (%)

  

0.038

No

24 (52.17%)

7 (26.92%)

 

Yes

22 (47.83%)

19 (73.08%)

 
  1. Continuous variables were analyzed using Mann–Whitney U two-sided statistics, and categorical variables were assessed with two-sided chi-square tests.
  2. AKI Acute kidney injury, eGFR estimated Glomerular filtration rate, hs-CRP Hypersensitive C-reactive protein, Max_Scr maximum serum creatinine after admission.