Table 1 Comparison results of EviDTI and baselines on the DrugBank dataset
From: Evidential deep learning-based drug-target interaction prediction
DrugBank | Accuracy (std) | Recall (std) | Precision (std) | MCC (std) | F1 score (std) | AUC (std) | AUPR (std) |
|---|---|---|---|---|---|---|---|
RF | 71.07 (1.34) | 73.08 (0.95) | 76.92 (1.42) | 51.23 (1.54) | 74.94 (0.92) | 83.03 (0.65) | 84.78 (0.67) |
NB | 52.90 (1.13) | 87.99 (1.77) | 51.71 (1.01) | 42.34 (3.24) | 65.13 (0.89) | 60.76 (1.24) | 59.37 (1.77) |
SVM | 78.02 (1.92) | 75.04 (2.93) | 73.86 (2.14) | 53.87 (1.29) | 74.39 (1.40) | 82.02 (1.62) | 82.85 (1.49) |
DeepConv-DTI | 79.50 (0.22) | 80.45 (0.21) | 79.30 (0.64) | 57.91 (0.61) | 79.87 (0.62) | 86.69 (0.22) | 86.28 (0.13) |
GraphDTA | 77.69 (0.11) | 78.77 (1.13) | 76.92 (1.05) | 55.41 (0.63) | 77.83 (1.18) | 83.62 (0.25) | 83.26 (0.18) |
MolTrans | 78.48 (0.17) | 81.97 (0.23) | 77.01 (0.35) | 55.65 (0.62) | 79.41 (0.73) | 85.98 (0.64) | 86.67 (0.12) |
HyperAttention | 80.85 (0.23) | 88.16 (0.15) | 77.09 (0.17) | 62.32 (0.42) | 82.26 (0.33) | 89.94 (0.14) | 88.95 (0.15) |
TransformerCPI | 79.01 (0.24) | 76.26 (0.36) | 80.47 (0.34) | 58.09 (0.22) | 78.31 (0.38) | 84.62 (0.33) | 84.23 (0.28) |
GraphormerDTI | 80.22 (1.07) | 82.05 (1.23) | 79.11 (0.91) | 60.48 (2.16) | 80.55 (1.02) | 88.63 (1.02) | 88.36 (0.99) |
AIGO-DTI | 81.88 (1.37) | 82.28 (2.69) | 81.26 (0.36) | 63.80 (2.78) | 81.74 (1.40) | 88.62 (1.02) | 88.44 (1.65) |
DLM-DTI | 82.13 (0.27) | 82.54 (1.91) | 81.68 (1.56) | 66.32 (0.55) | 81.08 (0.56) | 90.48 (0.48) | 90.20 (0.60) |
EviDTI | 82.02 (0.43) | 82.28 (1.03) | 81.90 (0.58) | 64.29 (1.05) | 82.09 (0.74) | 88.87 (0.73) | 88.45 (1.51) |
