Fig. 7: Reduced segregation of sensory responses in socially isolated group (SS). | Nature Communications

Fig. 7: Reduced segregation of sensory responses in socially isolated group (SS).

From: Differential impacts of social isolation and enriched environment on multi-sensory brain-wide functionality and network segregation

Fig. 7

Network segregation was calculated using area under the curve (AUC) values within the resting state networks observed during evoked sensory stimulation from SS (n = 6; blue), SG (n = 8; red), and EG (n = 8; green). The main network for each stimulation is outlined in a black box and shown as the mean AUC within the network. The main network is used to normalize response differences between networks for segregation values. Lower values indicate greater activation of the network relative to the main network, implying reduced segregation. Data are presented as mean ± SEM (Kruskal-Wallis test, corrected with Dunn’s test; *p < 0.05, **p < 0.01). (ORF: orofacial; Wh/FL: whisker/forelimb; HL/tr: hindlimb/trunk; PLN: posterior lateral network; TH: thalamic; OLF: olfactory). Source data are provided as a Source Data file.

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