Fig. 3: Characterization and scalability of the cell encapsulation pouch. | Nature Communications

Fig. 3: Characterization and scalability of the cell encapsulation pouch.

From: A continuously oxygenated macroencapsulation system enables high-density packing and delivery of insulin-secreting cells

Fig. 3

A Schematic illustration for the structure of a cell encapsulation pouch. B Representative digital images showing cell encapsulation pouches in various lengths and diameters, designed to accommodate different cell doses. The inset shows the round end of the pouch. C SEM images of the pouch surface and cross-section. The experiment was repeated independently at least five times with similar results. D Size distribution of PEBAX fibers. E Tensile testing of PEBAX cell encapsulation pouches (n = 3). F Digital images of a nitinol scaffold and a nitinol-reinforced pouch. Both were bent without kink. G Digital images demonstrating the ability of nitinol-reinforced pouches to reverse to their original structural form following twisting deformation. H Representative microscopy image showing the alginate impregnation onto the encapsulation pouch. The experiment was repeated independently at least ten times to prepare for in vivo study with similar results. Figure (E) was partly created in BioRender. Pham, T. (2025) https://BioRender.com/gzlonoy.

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