Table 1 Succinic acid production by metabolically engineered microorganisms using glucose as sole carbon source

From: Decompartmentalization of the yeast mitochondrial metabolism to improve chemical production in Issatchenkia orientalis

Microorganism

Titer (g/L)

Yield (g/g glucose)

Productivity (g/L/h)

Medium

pH

Reference

E. coli

114.0

0.91

3.25

Complex medium

6.6–7.0

74

E. coli

119.0

1.06

1.65

CSL

6.5

75

C. glutamicum

146

0.92

3.17

Mineral salts (BT)

6.6–7.0

76

C. glutamicum

152.2

0.85

0.95

Complex medium

7.0

77

Y. lipolytica

111.9 

0.79

1.80

Modified CM1

2.49

60

I. orientalis

104.28

0.85

0.97

SC-URA

3.0

This study

I. orientalis

101.86

0.80

0.94

CSL

3.0

This study

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