Fig. 4: PreMode and other methods’ performances in molecular mode-of-action prediction tasks. | Nature Communications

Fig. 4: PreMode and other methods’ performances in molecular mode-of-action prediction tasks.

From: PreMode predicts mode-of-action of missense variants by deep graph representation learning of protein sequence and structural context

Fig. 4

a Spearman correlations of PreMode in multiplexed deep mutational scan experiments of 8 genes compared to other methods, mean and standard error were calculated from five random training/testing splits. b Comparison of overall Spearman correlations of PreMode compared to other methods, mean and standard error were calculated by weighted average of mean and standard error in 8 experiments based on dataset sizes. c Comparison of overall Spearman correlations of PreMode compared to other methods under sub-sampled data, mean and standard error were calculated by weighted average of mean and standard error in 8 experiments based on dataset sizes.

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