Table 2 Replication of published variants

From: Large-scale GWAS of strabismus identifies risk loci and provides support for a link with maternal smoking

Original paper

RsID (gene)

OR (95%CI) in the original paper

OR in this study

P in the original paper

P in this study

MAF in the original paper

MAF in this study

Trait

10

rs2244352 (WRB)

1.41

1.01

2.84 × 10−9

0.02571

0.33

0.29

Strabismus

  

1.03

 

0.0065

 

0.29

Esotropia

  

1.04

 

0.0011

 

0.26

Exotropia

10

rs912759 (ADGRL4)

0.59

1.00

1.89 × 10−8

0.8899

0.47

0.49

Strabismus

  

1.01

 

0.1902

 

0.49

Esotropia

  

1.00

 

0.6978

 

0.49

Exotropia

11

rs75078292 (TSPAN10)

1.26

1.06

2.24 × 10−8

2.243 × 10−18

0.35

0.38

Strabismus

  

1.07

 

1.022 × 10−8

 

0.39

Esotropia

  

1.04

 

0.00161

 

0.39

Exotropia

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