Table 4 Two-sample MR to assess the effect of birth weight (BW) on strabismus risk

From: Large-scale GWAS of strabismus identifies risk loci and provides support for a link with maternal smoking

Trait

IVW BETA per 500 g increase of birth weight (SE)

IVW P value

OR per 500 g increase of birth weight (95%CI)

MR-Egger intercept (SE)

MR-Egger P value

MR-PRESSO BETA (SE)

MR-PRESSO P value

Strabismus

0.047 (0.032)

0.14

1.05 (0.98–1.12)

−0.0016 (0.0024)

0.52

0.048 (0.032)

0.14

Esotropia

0.091 (0.075)

0.22

1.10 (0.95–1.27)

−0.00094 (0.0056)

0.87

0.096 (0.075)

0.20

Exotropia

0.015 (0.071)

0.83

1.02 (0.88–1.17)

0.0019 (0.0053)

0.72

0.0074 (0.069)

0.91

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