Table 1 Demographic characteristics of enrolled participants for flow cytometry analysis

From: TLR4+group 2 innate lymphoid cells contribute to persistent type 2 immunity in airway diseases

 

IL-5⁻NP

IL-5+NP

P value

Participant number

9

29

–

Sex (male/female)

9/0

23/6

0.3031

Age (years), median (IQR)

45 (27-68)

51 (29-66)

0.4514

Asthma (%)

0 (0%)

15 (51.72%)

0.0060

Revision surgery (%)

2 (22.22%)

13 (44.83%)

0.2733

Tissue biomarker

 IL-13 (pg/mL), median (IQR)

80.48 (67.37-100.42)

196.52 (135.77-223.89)

0.0079

 IL-5 (pg/mL), median (IQR)

4.39 (3.245-5.83)

201.6 (60.5–330.99)

2.0 × 10-6

 IFN-γ (pg/mL), median (IQR)

27.83 (9.13-38.61)

19.58 (9.295–37.29)

0.9124

 IL-17 (pg/mL), median (IQR)

19.03 (6.545-99.55)

6.545(6.325–6.545)

0.0140

 ECP (ng/mL), median (IQR)

524.6 (230.9-1171)

5364 (3323–8467)

8.4 × 10-5

 eosinophils (%), median (IQR)

4.55 (1.88-12.03)

42.80 (26.81–65.55)

0.0001

  1. For dichotomous variables, a two-tailed Fisher exact test was performed to determine the difference between groups. Between-cluster differences of biomarkers and characteristics were compared by a two-tailed Mann-Whitney U test. NP, nasal polyps; IQR, interquartile range.
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