Table 1 sgRNA-targeting sequence for gene knockout

From: RIPK1 kinase drove brain microvascular endothelial cells death and blood-brain barrier disruption in neonatal Escherichia coli meningitis

Gene

sgRNA targeting sequence

Ripk1

GCTCTGCTGGGAAGCGAATC

Ripk3

TACACGAGTGATGGTTCGGT

Caspase-8

GCCTGGACTACATTCCGCAA

Caspase-1

TTATCCGTTCCATGGGTGA

Zbp1

GCAGGATTCTTTGTTCAAGG

Trif

GTAGGCCACGTCCCGCAGCG

Tnfr1

CTGATGGGGATACATCCATC

Tlr4

GGGGTTTCCTGTCAATATTA

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