Fig. 7: Co-evolution of rRNA and r-proteins.

The E. histolytica LSU is shown on the solvent side in the middle, and regions of rRNA and r-protein co-evolution are zoomed and shown in the surrounding area in roughly matching orientation. The rRNA (blue) is shown in ribbon and surface view with 80% transparency. The r-proteins in the ribbon (light blue) and extension/insertion (red) are shown. Central perturbance (CP) and peptide exit tunnel (PET) are labeled. A circle that is 50% transparent shows the location of PET in LSU. A full 3D model of r-protein with extensions is provided in Supplementary Fig. 13.