Fig. 3: Scope of gem-difluorides from sulfones generated via substitutions using alkenes as radical acceptors. | Nature Communications

Fig. 3: Scope of gem-difluorides from sulfones generated via substitutions using alkenes as radical acceptors.

From: Modular synthesis of CF2-containing compounds with PhSO2CF2H reagent through difluoromethylene radical anion synthon strategy

Fig. 3

Reaction conditions: 2 (0.5 mmol, 1.0 equiv), 1 (2.0 equiv), 2-NpSH (20 mol%), HCO2K (3.0 equiv), DMSO (4 mL), white LED, room temperature, 18 h. All yields are isolated yields. aK2CO3 (1.0 equiv) as an additive. bThe reaction was conducted on 0.2 mmol scale.

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