Fig. 4: Scope of gem-difluorides from sulfones with thiols as radical acceptors. | Nature Communications

Fig. 4: Scope of gem-difluorides from sulfones with thiols as radical acceptors.

From: Modular synthesis of CF2-containing compounds with PhSO2CF2H reagent through difluoromethylene radical anion synthon strategy

Fig. 4

Reaction conditions: 2 (0.5 mmol, 1.0 equiv), 1 (2.0 equiv), DBU (2.0 equiv), DMSO (4 mL), white LED, room temperature, 18 h. All yields are isolated yields. a1 (0.5 mmol, 1.0 equiv), 2 (2.0 equiv). bfac-Ir(ppy)3 (0.2 mol%) as an additive, blue LED instead of white LED. DBU = 1,8-diazabicyclo[5.4.0]undec-7-ene.

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