Fig. 5: The hierarchical tubulin folding pathway facilitated by the chaperonin TRiC.
From: Visualizing dynamic tubulin folding in chaperonin TRiC from nonnative nucleus to final native state
A The energy landscape of tubulin folding, showing the folding nucleus, intermediate states, and the fully folded tubulin positioned at distinct energy minima. B The hierarchical mechanism of tubulin folding, illustrating the sequential progression through a nonnative folding nucleus, three intermediate states, and the fully folded tubulin.
