Fig. 3: HFD exposure disrupts blastocyst metabolic gene expression. | Nature Communications

Fig. 3: HFD exposure disrupts blastocyst metabolic gene expression.

From: Maternal diet-induced alterations in uterine fluid sncRNAs compromise preimplantation embryo development and offspring metabolic health

Fig. 3

a Representative morphology of blastocysts in ND and HFD groups, scale bar = 20 μm, n = 3 biologically independent experiments. b Principal component analysis (PCA) of transcriptome profiles of blastocysts in the ND and HFD groups. c Differential gene expression in blastocysts of ND and HFD groups. NS not significant. d Top 10 enriched Gene Ontology (GO) terms among significantly altered genes. The red font signifies the metabolic pathways. n = 3, BP Biological Process, CC Cellular Component, MF Molecular Function. Statistical source data and precise P value are provided as in the Source Data file.

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