Fig. 4: MinD signaling modeling supports the hypothesis of a membrane diffusion drop due to buckling.

A Cartoon of the Min oscillatory system model, adapted from⁶¹. B Spatio-temporal evolution of MinD obtained in simulations of a growing filament. Top: Kymograph of a filament with an initial length of 50 μm growing for its doubling time (50 min). For \(t\in \left(0,20\right)\) min (dashed purple line), no buckling is implemented. For \(t\in \left(20,50\right)\) min (solid purple line), the membrane diffusion coefficients of proteins are set to a 30% of their values within a 3 μm-wide band (Methods). Bottom: Temporal averages of MinD (arbitrary units) for a period of 20 minutes immediately before (dashed purple line) and a period of 30 minutes immediately after (solid purple line) the diffusion drop within the region delimited by the white dashed lines shown in the kymograph. The green line delimits the region where the simulated curvature reaches ∣κ∣ ~1μm⁻¹ as represented in the inset.