Extended Data Fig. 6: Enzymatic activities of KATs from two F1 progenies.

(a) Structure and location of the 5’UTR PRG4, 3’UTR deletion and five Amino acid substitutions that co-segregated with the picein trait in two F1 progenies. (b-c) In vitro enzyme assays showing the content of piceol (b) and 4HBA (c) produced by different genotype KATs in two F1 progenies. Data are presented as means ± SEM from three independent experiments. The P values were calculated via two-tailed Student’s t-tests.