Fig. 2: The effects of PCC1 on physiological parameters and HIS cells of aged mice. | npj Aging

Fig. 2: The effects of PCC1 on physiological parameters and HIS cells of aged mice.

From: Single-cell profiling unveils a geroprotective role of Procyanidin C1 in hematopoietic immune system via senolytic and senomorphic effects

Fig. 2

A Schematic diagram of experimental design for standard diet or PCC1-added diet and the scRNA-seq analysis of HIS cells. B Line plot showing the weights of mice of the indicated groups throughout the four-month period. C Bar plot showing mean and max grip strength of mice measured every month over a four-month period. Violin plot showing the SASP score (D) and the inflammatory response score (E) of the indicated groups. FCM histograms (left) and column charts (right) showing the proportion of B cells (F) and LSK cells (G) among three groups (n = 5/group). Significance was calculated using one-way ANOVA test (C, F, G) or two-tailed unpaired t-test (D, E); ns, not significant, *P < 0.01, **P < 0.01, ***P < 0.001, ****P < 0.0001.

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