Table 2 Cases and ASR of YLDs and YLLs with EAPC for LBMD, globally and by 21 GBD regions
Characteristics | 1990 | 2021 | 1990–2021 | 1990 | 2021 | 1990–2021 | ||||
---|---|---|---|---|---|---|---|---|---|---|
YLDs cases No. (95% CI) | ASR per 100,000 No. (95% CI) | YLDs cases No. (95% CI) | ASR per 100,000 No. (95% CI) | EAPC No. (95% CI) | YLLs cases No. (95% CI) | ASR per 100,000 No. (95% CI) | YLLs cases No. (95% CI) | ASR per 100,000 No. (95% CI) | EAPC No. (95% CI) | |
Global | 2136261 (1516091 to 2880897) | 623.50 (441.30 to 841.08) | 4495820 (3152692 to 6128799) | 567.51 (398.07 to 773.51) | −0.36(−0.39 to −0.32) | 1512006 (1227605 to 1732919) | 450.92 (364.06 to 518.75) | 3267682 (2487786 to 3854916) | 411.69 (313.77 to 485.32) | −0.21(−0.27 to −0.16) |
Andean Latin America | 4146 (2970 to 5482) | 252.22 (180.24 to 333.75) | 13356 (9352 to 18054) | 261.01 (182.81 to 352.72) | 0.12(0.03 to 0.21) | 4636 (3708 to 5581) | 286.15 (227.40 to 346.07) | 13327 (9783 to 17277) | 260.31 (191.15 to 337.40) | −0.32(−0.42 to −0.23) |
Australasia | 20573 (14132 to 28488) | 894.17 (613.21 to 1241.07) | 53729 (36735 to 74590) | 985.02 (676.22 to 1369.84) | 0.53(0.43 to 0.63) | 5910 (4709 to 6857) | 255.32 (203.05 to 296.62) | 17726 (12905 to 21777) | 283.60 (210.29 to 345.75) | 1.22(0.95 to 1.48) |
Caribbean | 7863 (5458 to 10643) | 363.93 (250.65 to 494.07) | 21510 (14527 to 29775) | 418.31 (283.71 to 578.33) | 0.39(0.3 to 0.49) | 8622 (6986 to 10097) | 410.01 (326.84 to 484.35) | 20701 (15640 to 25537) | 390.90 (297.82 to 480.81) | −0.58(−0.78 to −0.39) |
Central Asia | 14890 (10608 to 20087) | 318.84 (226.86 to 430.15) | 20790 (14691 to 28267) | 276.56 (195.20 to 375.82) | −0.26(−0.34 to −0.17) | 7264 (6034 to 8050) | 155.60 (128.99 to 172.71) | 7969 (6502 to 9119) | 106.99 (87.19 to 122.52) | −0.8(−1.1 to −0.5) |
Central Europe | 133942 (95024 to 180364) | 916.17 (647.77 to 1234.66) | 146465 (101320 to 202176) | 615.58 (426.41 to 851.24) | −1.39(−1.43 to −1.35) | 78604 (65952 to 87316) | 563.49 (467.14 to 631.13) | 54188 (43471 to 62406) | 213.73 (172.75 to 245.45) | −3.53(−3.76 to −3.31) |
Central Latin America | 37765 (27146 to 50090) | 580.69 (415.80 to 770.90) | 86334 (60757 to 116095) | 384.61 (270.56 to 517.07) | −1(−1.17 to −0.83) | 26492 (22377 to 29140) | 432.71 (361.24 to 480.16) | 45617 (36522 to 53462) | 204.27 (163.53 to 239.43) | −2.43(−2.64 to −2.23) |
Central Sub-Saharan Africa | 3988 (2896 to 5272) | 256.95 (185.79 to 339.44) | 10390 (7538 to 13704) | 266.99 (192.76 to 351.94) | 0.13(0.08 to 0.19) | 11527 (8573 to 15278) | 771.87 (566.91 to 1043.54) | 29276 (20623 to 40464) | 769.52 (535.78 to 1081.80) | −0.01(−0.03 to 0.02) |
East Asia | 289064 (207696 to 384340) | 431.76 (309.35 to 573.93) | 867637 (606172 to 1189147) | 450.63 (314.27 to 617.66) | −0.21(−0.59 to 0.17) | 226375 (176090 to 300725) | 381.61 (292.55 to 506.68) | 583711 (363216 to 795871) | 315.19 (193.11 to 431.64) | −0.34(−0.7 to 0.02) |
Eastern Europe | 193180 (137265 to 262158) | 605.15 (429.42 to 822.16) | 199246 (138875 to 276070) | 498.94 (347.83 to 691.95) | −0.81(−1.09 to −0.52) | 65713 (55702 to 71482) | 208.80 (175.84 to 228.15) | 65080 (53360 to 74830) | 161.80 (132.81 to 186.15) | −1.44(−1.79 to −1.1) |
Eastern Sub-Saharan Africa | 12919 (9445 to 17020) | 259.50 (189.02 to 341.42) | 30413 (22110 to 40219) | 262.26 (190.03 to 346.53) | 0.02(−0.01 to 0.06) | 43806 (34391 to 54430) | 912.52 (705.88 to 1152.30) | 87996 (68933 to 108514) | 792.56 (609.07 to 988.71) | −0.59(−0.64 to −0.53) |
High-income Asia Pacific | 119493 (83356 to 164653) | 614.58 (427.95 to 847.51) | 254336 (175287 to 353057) | 506.71 (350.30 to 705.14) | −0.77(−0.89 to −0.66) | 38189 (31417 to 43845) | 199.33 (162.60 to 229.75) | 67537 (46104 to 84595) | 105.26 (75.85 to 129.21) | −2.58(−2.73 to −2.43) |
High-income North America | 255800 (175684 to 354899) | 687.42 (472.03 to 955.67) | 581912 (401062 to 813134) | 875.36 (604.01 to 1224.04) | 0.87(0.79 to 0.94) | 78122 (62473 to 87876) | 205.19 (165.05 to 229.86) | 228108 (175768 to 262942) | 318.78 (249.75 to 363.70) | 1.67(1.57 to 1.76) |
North Africa and Middle East | 43982 (31567 to 58187) | 357.12 (256.32 to 471.89) | 112050 (79442 to 151581) | 342.51 (242.57 to 463.17) | −0.11(−0.2 to −0.02) | 42237 (33111 to 52713) | 368.72 (283.43 to 469.38) | 82063 (63231 to 102573) | 266.49 (201.89 to 337.00) | −0.93(−0.99 to −0.86) |
Oceania | 800 (575 to 1065) | 451.90 (323.06 to 602.13) | 2764 (1993 to 3664) | 619.46 (445.60 to 820.33) | 0.94(0.86 to 1.03) | 654 (426 to 974) | 400.38 (262.01 to 599.94) | 1665 (1076 to 2441) | 382.41 (244.66 to 571.56) | −0.06(−0.15 to 0.04) |
South Asia | 270413 (192895 to 362057) | 741.16 (526.78 to 992.43) | 840173 (595504 to 1130345) | 753.81 (532.96 to 1013.61) | −0.02(−0.08 to 0.04) | 414105 (279103 to 526023) | 1142.47 (767.53 to 1463.34) | 1201910 (863204 to 1491219) | 1079.51 (773.01 to 1351.13) | −0.19(−0.33 to −0.04) |
Southeast Asia | 78661 (56868 to 104427) | 409.85 (295.66 to 543.53) | 194850 (139501 to 260921) | 369.55 (263.98 to 494.13) | −0.49(−0.54 to −0.44) | 118617 (77683 to 152718) | 628.87 (396.59 to 827.36) | 245282 (166781 to 314469) | 473.79 (313.98 to 613.75) | −1.14(−1.29 to −0.99) |
Southern Latin America | 26047 (18742 to 34780) | 598.92 (430.54 to 799.82) | 50269 (35325 to 68516) | 567.07 (398.53 to 774.35) | −0.1(−0.16 to −0.04) | 10978 (9089 to 12525) | 261.03 (214.56 to 298.84) | 16447 (13034 to 19108) | 175.08 (139.73 to 202.72) | −0.73(−0.92 to −0.55) |
Southern Sub-Saharan Africa | 6251 (4532 to 8239) | 261.08 (189.24 to 343.96) | 8678 (6261 to 11564) | 165.85 (119.40 to 220.87) | −1.62(−1.68 to −1.56) | 6112 (4787 to 7703) | 259.04 (201.00 to 328.33) | 12993 (10621 to 15437) | 245.91 (199.35 to 294.58) | −0.22(−0.58 to 0.14) |
Tropical Latin America | 38967 (27767 to 51665) | 525.90 (372.98 to 698.49) | 111070 (77829 to 149774) | 459.58 (322.18 to 619.67) | −0.46(−0.55 to −0.36) | 24353 (20348 to 27052) | 345.97 (284.34 to 388.46) | 80012 (62272 to 93237) | 330.18 (257.69 to 384.15) | 0.39(0.06 to 0.72) |
Western Europe | 560343 (387178 to 768478) | 879.77 (605.65 to 1209.30) | 850620 (577696 to 1173332) | 833.65 (568.42 to 1151.74) | −0.06(−0.12 to 0) | 255019 (203524 to 290664) | 385.99 (307.49 to 440.58) | 315089 (231203 to 376142) | 254.39 (192.03 to 298.84) | −1.1(−1.36 to −0.83) |
Western Sub-Saharan Africa | 17176 (12480 to 22661) | 276.64 (200.42 to 364.94) | 39228 (28341 to 51999) | 292.79 (210.50 to 388.01) | 0.2(0.16 to 0.24) | 44671 (34447 to 55404) | 735.52 (562.16 to 922.25) | 90985 (68134 to 115709) | 695.73 (520.99 to 884.43) | −0.2(−0.26 to −0.13) |