Fig. 2: Associations between biological aging acceleration and disease transition hazards of atrial fibrillation and dementia.

AF atrial fibrillation, HR hazard ratio, CI confidence interval, SD standard deviation. Hazard ratios of associations between biological aging acceleration with different transition patterns of atrial fibrillation and dementia, controlling for sex, ethnicity, education, income, employment, alcohol consumption, physical activity, current smoking, chronic kidney disease, hypertension, diabetes, and cardiovascular diseases. Sample thirds were used to categorize the low, moderate, and high PhenoAge acceleration.