Fig. 3: Dose-response curves of associations between biological aging acceleration and hazards of certain transition patterns of atrial fibrillation and dementia.

AF atrial fibrillation, HR hazard ratio, CI confidence interval, SD standard deviation. Restricted cubic spline models were applied for depicting dose-response relationships, with three knots fixed at the 10th, 50th and 90th percentiles. Solid lines represent point estimates and shadows represent 95% confidence limits.