Fig. 5: Associations between specific microbes and individual metabolites in each disease.

a Heatmap showing the overall pattern of correlation between top microbial taxa (rows) and metabolites (columns) in factors identified by NMFGOT for GC, ESRD and IBD (p-value < 0.05). b Correlation network for significantly and stability-selected metabolites and microbial taxa in GC and ESRD. The red nodes represent metabolites, the blue nodes represent microbes. Edges represent metabolite-microbe associations. The red line indicates positive correlation, and green line indicates negative correlation.