Table 2 Examples of efflux and uptake transporters identified in human cervicovaginal tissues

From: Vaginal pharmacomicrobiomics modulates risk of persistent and recurrent bacterial vaginosis

Efflux transporters

Uptake transporters

ATP-binding cassette (ABC)

Solute carrier (SLC)

Solute carrier organic anion (SLCO)

P-glycoprotein (P-gp)156,157

Sodium/hydrogen exchanger-1 (NHE1/SLC9A1)161

Organic anion transporter (OAT)-2156

Multidrug resistance protein (MRP) – MRP1, MRP4, MRP5, MRP7156,157

Monocarboxylate transporter-1 (MCT-1/SLC16A1)218, MCT-4/SLC16A3158

Organic anion transporting polypeptides (OATP): OATP-D/SLCO3A1, OATP-E/ SLCO4A1156

Breast cancer resistance protein (BCRP)156,157

Organic cation transporter-2 (OCT2/SLC22A2), -3 (OCT3/SLC22A3)156

 

ATP-binding cassette (ABC) sub-family G member 1 (ABCG1)158

Concentrative nucleoside transporter 3 (CNT3/ SLC28A2)164

 
 

Equilibrative nucleoside transporter (ENT1/ SLC29A1)156

 
 

Nucleotide sugar transporter family (SLC35E4)158

 
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